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Chemistry 125A: Freshman Organic Chemistry I - Lecture 30: Esomeprazole as an Example of Drug Testing and Usage - Professor J. Michael McBride

Lecture 30: Esomeprazole as an Example of Drug Testing and Usage

The chemical mode of action of omeprazole is expected to be insensitive to its stereochemistry, making clinical trials of the proposed virtues of a chiral switch crucial. Design of the clinical trials is discussed in the context of marketing. Otolaryngologist Dr. Dianne Duffey provides a clinician's perspective on the testing and marketing of pharmaceuticals, on the FDA approval process, on clinical trial system, on off-label uses, and on individual and institutional responsibility for evaluating pharmaceuticals.

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