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Chemistry 125A: Freshman Organic Chemistry I - Lecture 27: Communicating Molecular Structure in Diagrams and Words - Professor J. Michael McBride

Lecture 27: Communicating Molecular Structure in Diagrams and Words

It is important that chemists agree on notation and nomenclature in order to communicate molecular constitution and configuration. It is best when a diagram is as faithful as possible to the 3-dimensional shape of a molecule, but the conventional Fischer projection, which has been indispensable in understanding sugar configurations for over a century, involves highly distorted bonds. Ambiguity in diagrams or words has led to multibillion-dollar patent disputes involving popular drugs. International agreements provide descriptive, unambiguous, unique, systematic "IUPAC" names that are reasonably convenient for most organic molecules of modest molecular weight.

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