ACTIVITIES | POINTS |
---|---|

Three one-hour exams | 100 (each) |

Homework | 100 |

Final exam | 200 |

### Course Description

This subject deals primarily with equilibrium properties of macroscopic systems, basic thermodynamics, chemical equilibrium of reactions in gas and solution phase, and rates of chemical reactions. Acknowledgements The material for 5.60 has evolved over a period of many years, and therefore several faculty members have contributed to the development of the course contents. The following are known to have assisted in preparing the lecture notes available on OpenCourseWare: Emeritus Professors of Chemistry: Robert A. Alberty, Carl W. Garland, Irwin Oppenheim, John S. Waugh. Professors of Chemistry: Moungi Bawendi, John M. Deutch, Robert W. Field, Robert G. Griffin, Keith A. Nelson, Robert J. Silbey, Jeffrey I. Steinfeld. Professor of Bioengineering and Computer Science: Bruce Tidor. Professor of Chemistry, Rice University: James L. Kinsey. Professor of Physics, University of Illinois: Philip W. Phillips.

### About Prof. Keith A. Nelson, Prof. Moungi Bawendi

Prof. Moungi Bawendi received his A.B. in 1982 from Harvard University and his Ph.D. in chemistry in 1988 from The University of Chicago. His PhD research focused on the theory of polymers and the experimental infrared spectroscopy of molecular ions of astrophysical interest. This was followed by two years of postdoctoral research at Bell Laboratories, working with Dr. Louis Brus, where he began his studies on nanomaterials. Bawendi joined the faculty at MIT in 1990, becoming Associate Professor in 1995 and Professor in 1996. He has followed an interdisciplinary research program that aims at probing the science and developing the technology of chemically synthesized nanocrystals. Among his awards are MIT graduate and undergraduate teaching awards, the Coblentz Award for Molecular Spectroscopy, the Harvard Chemistry Department Wilson Prize, the Raymond and Beverly Sackler Prize in the Physical Sciences, the EO Lawrence award in Materials Chemistry from the US Department of Energy, the Fred Kavli Distinguished Lecture in Nanoscience from the Materials Research Society, and the American Chemical Society Award in Colloid and Surface Chemistry. Prof. Bawendi is a fellow of the American Association for the Advancement of Science, a fellow of the American Academy of Arts and Sciences, and a member of the National Academy of Sciences.

Note: Contents for this page are Licensed from http://ocw.mit.edu under the Creative Commons Attribution Share-Alike license.

## Course Meeting Times

Lectures: 3 sessions / week, 1 hour / session

Recitations: 2 sessions / week, 1 hour / session

## Overview

This subject deals with both chemical thermodynamics and chemical kinetics. The material that will be covered in this subject is intended to provide you with the tools and understanding to handle basic problems involving chemical systems at equilibrium and rates of simple chemical reactions.

## Textbook

Silbey, R., R. Alberty, and M. Bawendi.

*Physical Chemistry*. 4th ed. New York, NY: John Wiley & Sons, 2004. ISBN: 9780471215042.## Other Resources

Atkins, P., and J. de Paula.

*Physical Chemistry*. 7th ed. New York, NY: W.H. Freeman and Company, 2001. ISBN: 9780716735397.Castellan, G.

*Physical Chemistry*. 3rd ed. Reading, MA: Addison-Wesley, 1983. ISBN: 9780201103861.Houston, P.

*Chemical Kinetics and Reaction Dynamics*. New York, NY: McGraw-Hill, 2001. ISBN: 9780072435375.## Examinations

There will be three one-hour examinations during the term and a final examination. The exams will be closed-notes and closed-book unless otherwise announced. Tutorial reviews will be held prior to each exam.

## Homework

Problems will be assigned every week. Late problem sets are not accepted. Homework will be graded by the recitation instructor and returned in recitation.

## Grading

Grades for the subject will be based on a total of 600 points:

ACTIVITIES POINTS Three one-hour exams 100 (each) Homework 100 Final exam 200 ## Calendar

SES # TOPICS KEY DATES 1 State of a system, 0 ^{th}law, equation of state2 Work, heat, first law 3 Internal energy, expansion work 4 Enthalpy 5 Adiabatic changes Problem set 1 due 6 Thermochemistry 7 Calorimetry 8 Second law Problem set 2 due 9 Entropy and the Clausius inequality 10 Entropy and irreversibility 11 Fundamental equation, absolute S, third law Problem set 3 due 12 Criteria for spontaneous change First hour exam 13 Gibbs free energy 14 Multicomponent systems, chemical potential 15 Chemical equilibrium 16 Temperature, pressure and K _{p}Problem set 4 due 17 Equilibrium: application to drug design 18 Phase equilibria — one component 19 Clausius-Clapeyron equation Problem set 5 due 20 Phase equilibria — two components Second hour exam 21 Ideal solutions 22 Non-ideal solutions 23 Colligative properties 24 Introduction to statistical mechanics Problem set 6 due 25 Partition function (q) — large N limit 26 Partition function (Q) — many particles 27 Statistical mechanics and discrete energy levels Problem set 7 due 28 Model systems 29 Applications: chemical and phase equilibria Problem set 8 due 30 Introduction to reaction kinetics Third hour exam 31 Complex reactions and mechanisms 32 Steady-state and equilibrium approximations 33 Chain reactions 34 Temperature dependence, E _{a}, catalysisProblem set 9 due 35 Enzyme catalysis 36 Autocatalysis and oscillators Final exam Lectures Thermodynamics & Kinetics - Lecture 1 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 2 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 3 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 4 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 5 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 6 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 7 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 8 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 9 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 10 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 11 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 12 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 13 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 14 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 15 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 16 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 17 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 18 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 19 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 20 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 21 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 22 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 23 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 24 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 25 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 26 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 27 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 29 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 30 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 31 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 32 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 33 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 34 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 35 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Thermodynamics & Kinetics - Lecture 36 - Prof. Keith A. Nelson, Prof. Moungi Bawendi View Description Type Link Exam 1 Information Download Click Exam 2 Information Download Click Exam 3 Information Download Click Final exam review Download Click Math review for final Download Click Description Type Link Course Materials Download Download Click Lecture Note 1 - State of a system, 0th law, equation of state Download Click Lecture Note 2 - Work, heat, first law Download Click Lecture Note 3 - Internal energy, expansion work Download Click Lecture Note 4 - Enthalpy Download Click Lecture Note 5 - Adiabatic changes Download Click Lecture Note 6 - Thermochemistry Download Click Lecture Note 7 - Calorimetry Download Click Lecture Note 8 - Second law Download Click Lecture Note 9 - Entropy and the Clausius inequality Download Click Lecture Note 10 - Entropy and irreversibility Download Click Lecture Note 11 - Fundamental equation, absolute S, third law Download Click Lecture Note 12 - Criteria for spontaneous change Download Click Lecture Note 13 - Gibbs free energy Download Click Lecture Note 14 - Multicomponent systems, chemical potential Download Click Lecture Note 15 - Chemical equilibrium Download Click Lecture Note 16 - Temperature, pressure and Kp Download Click Lecture Note 17 - Equilibrium: application to drug design Download Click Lecture 18 - Phase equilibria — one component Download Click Lecture Note 19 - Clausius-Clapeyron equation Download Click Lecture Note 20 - Phase equilibria — two components Download Click Lecture Note 21 - Ideal solutions Download Click Lecture Note 22 - Non-ideal solutions Download Click Lecture Note 23 - Colligative properties Download Click Lecture Note 24 - Introduction to statistical mechanics Download Click Lecture Note 25 - Partition function (q) — large N limit Download Click Lecture Note 26&27 Partition function (Q) — many particles Download Click Lecture Note 28 - Model systems Download Click Lecture Note 29 - Applications: chemical and phase equilibria Download Click Lecture Note 30 - Introduction to reaction kinetics Download Click Lecture Note 31 - Complex reactions and mechanisms Download Click Lecture Note 32 - Steady-state and equilibrium approximations Download Click Lecture Note 33 - Chain reactions Download Click Lecture Note 34 - Temperature dependence, Ea, catalysis Download Click Lecture Note 35 - Enzyme catalysis Download Click