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Organic & Biomaterials Chemistry

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  • Course Description

    This course covers principles of materials chemistry common to organic materials ranging from biological polypeptides to engineered block copolymers. Topics include molecular structure, polymer synthesis reactions, protein-protein interactions, multifunctional organic materials including polymeric nanoreactors, conducting polymers and virus-mediated biomineralization. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementation of any of the material presented. Legal Notice

    About Prof. Krystyn Van Vliet, Prof. Michael Rubner, Prof. Angela M.Belcher

    Prof. Krystyn Van Vlie is an Assistant Professor of Materials Science and Engineering Jointly appointed in Biological Engineering. Angela M. Belcher is a materials scientist, biological engineer, and W.M. Keck Professor of Energy at the Massachusetts Institute of Technology (MIT) in Cambridge, Massachusetts, United States.[1] She is director of the Biomolecular Materials Group at MIT and a 2004 MacArthur Fellow.

    Note: Contents for this page are Licensed from under the Creative Commons Attribution Share-Alike license.

    Massachusetts Institute of Technology

    Course Code

    Date Taught
    Fall 2005

    Undergraduate (First Year)
  • Course Meeting Times

    Lectures: 3 sessions / week, 1 hour / session

    Recitations: 1 session / week, 1 hour / session

    Labs: 1 session / week, 4 hours / session

    Grading Policy

    Students are encouraged to work together on problem sets and laboratory experiment analysis, but must prepare write-ups for these assignments individually. Students must work independently on exams. Grades will be distributed as follows:

    ACTIVITIES                          PERCENTAGES

    Six Problem Sets                      10%

    Laboratory Experiments             30%

    Three Exams ( Including Final )  60%(20% each)

    Laboratory Grading

    As will be discussed at the first recitation, each laboratory includes a short quiz at the start of the session, and an independent written assignment. Prof. Van Vliet grades all quizzes and laboratory assignments, and will handle excused / unexcused absences related to the laboratory experiments. Late arrivals and unexcused absences receive a zero for that laboratory experiment.

    1 Introduction  
    2 Chemical Bonding  
    3 Bonding in Organic Systems  
    4 Resonance  
    5 Synthetic Polymer Structure I  
    6 Synthetic Polymer Structure II  
      Lab 1A  
    7 Biological Structure I  
      Lab 1B  
    8 Biological Structure II Problem set 1 due
    9 Basic Reaction Types  
    10 Introduction to Macromolecular Systems Lab 1 due
    11 Step Growth Polymerization I Problem set 2 due
    12 Step Growth Polymerization II  
    13 Step Growth Reaction Kinetics I  
      Exam 1 Problem set 3 due
    14 Exam Review / Step Growth I  
    15 Step Growth Reaction Kinetics II  
    16 Step Growth Reaction Kinetics III  
      Lab 2A  
    17 Functional Group Reactions I Lab 1R due
      Lab 2B  
    18 Functional Group Reactions II  
    19 Enzymes I  
    20 Enzymes II  
    21-22 Functional Group Reactions II  
    23 Chain Growth Polymerization I  
    24-25 Chain Growth Polymerization II  
      Lab 3A  
    26 Chain Growth Reaction Kinetics  
      Lab 3A (cont.)  
      Exam 2  
    27 Exam Review / Protein Folding Lab 3 due
    28 Lipid Structure/Function I  
    29 Carbohydrate Structure/Function  
    30-31 Viruses as Materials  
      Lab 4A  
    32 Conducting Polymers I  
      Lab 4B  
    33 Conducting Polymers II  
    34 Self Assembly in Solution Lab 4 due
    35 Self Assembly on Surfaces I  
    36 Self Assembly on Surfaces II  
    37 Toolbox  
    38 Last Class Lecture  
  • DescriptionTypeLink
    Nanoreactors and BacteriaDownloadClick
    Interfacial PolymerizationDownloadClick
    Engineering DNA via Restriction EnzymesDownloadClick
    Viruses as MaterialsDownloadClick
  • DescriptionTypeLink
    Problem Set 1DownloadClick
    Problem Set 1 SolutionDownloadClick
    Problem Set 2DownloadClick
    Problem Set 2 SolutionDownloadClick
    Problem Set 3DownloadClick
    Problem Set 3 SolutionDownloadClick
    Practice Set ADownloadClick
    Practice Set A SolutionDownloadClick
    Practice Set BDownloadClick
    Practice Set B SolutionDownloadClick
    Practice Set CDownloadClick
    Practice Set CDownloadClick
  • DescriptionTypeLink
    Practice Quiz 1DownloadClick
    Practice Quiz 1 SolutionDownloadClick
    Quiz 1DownloadClick
    Quiz 1 SolutionDownloadClick
    Practice Quiz 2DownloadClick
    Practice Quiz 2 SolutionDownloadClick
    Quiz 2DownloadClick
    Quiz 2 SolutionDownloadClick
    Final ExamDownloadClick
  • DescriptionTypeLink
    Course IntroductionDownloadClick
    Gram-Positive and Gram-Negative BacteriaDownloadClick
  • DescriptionTypeLink
    Download Course MaterialsDownloadClick
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