Dr David Alker, David Alker Associates
This lecture aims to illustrate how the field of medicinal chemistry has led and will continue to lead to the discovery of new medicines which impact millions of lives worldwide. Using specific examples, a description wil be given of the processes involved in taking the knowledge of a modern day disease mechanism (such as cancer, AIDS etc.). and applying problem-solving techniques to design molecules to interact with specific biological targets, thereby saving lives and improving quality of life. This talk will highlight how diverse technologies (such as robotics used originally in the car industry and supercomputers) and ground-breaking discoveries in other scientific fields (biology, analytics, formulation, large-scale chemistry, engineering) are co-ordinated in the design of new therapeutic agents, with the emphasis being on how chemistry is the core science which makes this possible.