29th SCI Process Development Symposium

Dec 07, 2011 - Dec 09, 2011
Churchill College, Cambridge, UK

Churchill College, Cambridge, UK
07 December - 09 December 2010, 11.00 - 12.50
Organised by SCI's Fine Chemicals Group

The area of Process Development continues to be a challenging and important area for the research into and application of modern synthetic organic chemistry, as well as enabling technologies.

Process Development is the application of chemistry to the scale up of new synthetic processes from the laboratory, through pilot plant to full scale commercial manufacture and into life cycle management. It is an extremely broad discipline, crossing the boundaries between synthetic organic chemistry, process technology and chemical engineering.

Who should attend?
This meeting brings together experts from across the entire spectrum of the discipline to present state of the art process development. As an established and well attended meeting, the process development symposium offers an excellent opportunity for networking between like-minded process scientists of all levels of experience and from all areas of the chemical industry.

An exhibition will run alongside the conference during refreshment breaks, for companies and related organisations who may wish to exhibit. For further information and prices please email

Wednesday 7 December

  Registration and refreshments
  Opening remarks
  Process development of GSK1120212B: A novel MEK inhibitor for the treatment of cancer
Dr Richard Ward, GlaxoSmithKline, UK
14.10  Flow chemistry dealing with solids
Prof Xiong-Wei Ni, NiTech Solutions Ltd, UK
14:50  Semisynthetic artemisinin: path to industrial production
Dr Joel Turconi, Sanofi-Aventis, France
15:30  Refreshments
16:10  Large scale synthesis of diphenylalanine
Dr Justine Peterson, Dr Reddy's, UK
16.50  With efficient catalysis towards a commercial synthesis of edaglitazone and aleglitazar
Dr Michelangelo Scalone, F. Hoffman-La Roche AG, Switzerland
17:30  Discussion and close

17.45  Drinks reception sponsored by Dr Reddy's

19.00  Dinner for residents

Thursday 8 December

  Development of an enantioselective multikilogram synthesis of a HCV polymerase inhibitor
Dr Jeremy Scott, Merck, UK

  Industrial biotechnology in the speciality chemicals industry
Dr Surinder P Chahal, Croda, UK
  Model based process development
Dr Wilfried Hoffman, Pfizer, UK
11:30  A Case History - full title to be announced
Dr Chris Wallis, GlaxoSmithKline (retired), UK
12:10  Lunch
13:10  Going against the flow?
Dr Patrick Delaney, Peakdale, UK
13:50  Isotope labelling provides new possibilities in process development
Dr Eva Jakobssen, AstraZeneca, Sweden
14:30  Refreshments
15:00  Process development of an oxazolidinone antibiotic, TR-701FA
Dr Robert Duguid, AMRI, USA
15:40  GlaxoSmithKline, AstraZeneca, Syngenta and Pfizer Prize for process chemistry research 2011
Winner to be announced

16.40  Discussion and close
17.30  Drinks reception 
19:00  Symposium dinner

Friday 9 December

  Chiral amines by asymmetric hydrogenation processes
Dr André de Vries, DSM, The Netherlands
  Estimating the comparative costs of batch and continuous hydrogenation
Dr Fred Hancock, Johnson Matthey, UK
  Development of methods for the systematic exploration of chemical space
Prof Adam Nelson, University of Leeds, UK
11:30  Mechanistic chemistry from lab to plant
Dr Colin Brennan, Syngenta, UK
12:10  Practical catalytic enantioselective syntheses of 5-phenylbicyclo [2.2.2]oct-5-en-2-one. A concise entry into chiral diene ligands
Dr Stefan Abele, Actelion, Switzerland
12:50  Close followed by lunch

To view the full programme, click here.


Churchill College is one of 31 Colleges that comprises the University of Cambridge. Founded in 1960, it is a 15 minute walk from the centre of Cambridge. Despite the concentration of hi-tech and science industries around Cambridge, the centre still retains the atmosphere of a small town, renowned for the many university colleges and places of interest. Further information about Cambridge and alternative accommodation can be found on the following website:

Travel to Cambridge is convenient by road or rail. Churchill College is on Storey's Way, off the A1303 one mile west of the city centre and close to the M11 motorway. There are frequent train services to Cambridge from London King's Cross and Liverpool Street Stations. The nearest international airport is London Stansted (30 miles) which has rail and coach links to Cambridge. From London Heathrow and Gatwick Airports there are express rail links to central London for onward rail journeys as above. There are also coach links from both airports direct to Cambridge.

A map will be sent to all delegates with the confirmation email

Accommodation for delegates at the college comprises either single study ensuite or single study standard bedrooms. Rooms will be allocated on a first-come, first served basis.

The accommodation package is for two nights - Wednesday 7 and Thursday 8 December and includes Full English or Continental breakfast plus an evening meal on Wednesday 8 December. Rooms must be vacated by 10.00am on the day of departure. Luggage storage will be available. Those not wishing to stay in college accommodation can book accommodation directly through

Please note: Bedrooms at the college will be available from 14.00 on the day of arrival.

Organising Committee
Dr John Carey, Reckitt Benckiser, UK
Dr Louis Diorazio,AstraZeneca, UK
Dr Alan Ironmonger, GlaxoSmithKline, UK
Dr David Lathbury, AMRI Global, UK
Mr Alan Pettman, Pfizer, UK
Mr Scott Taylor, Syngenta, UK

Churchill College, Cambridge, UK
Please click here for a location map.

Delegate Fees
Earlybird fees - before 14 October
GB£440 . . . . . . . . SCI Member
GB£250. . . . . . . . SCI Student/ Subsidised Member
GB£495. . . . . . . . Non Member

Standard fees - after 14 October
GB£480. . . . . . . . SCI Member
GB£275. . . . . . . . SCI Student/ Subsidised Member
GB£535. . . . . . . . Non Member

Accommodation fees

GB £170. . . . . . . . Single Ensuite Room (with private bathroom)
GB£135.. . . . . . . . Single Standard Room (with shared bathroom)

For more information, please contact:

Conference Team
T: +44 (0)20 7598 1561
F: +44 (0)20 7235 7743

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