Entretien avec Ada Yonath

May 21, 2011
Cité des sciences et de l'industrie, Paris

Ada Yonath
Professor at the Weizmann Institute of Science, Israel, Nobel Prize in Chemistry 2009 with Thomas Steitz and Venkatraman Ramakrishnan, Ada Yonath was rewarded for her work on identifying the molecular structure of the ribosome.



Amazing ribosome ! Discovering a key organelle in the living world.

At the of heart of cells, between DNA, RNA and proteins, activates the key organelle of genetic translation, the Ribosome. Ada Yonath has reconstructed the precise structure of ribosomes. And now everything is visible in 3D simulation, using the techniques of crystallography and moving images.
Dive into the center of the cell to watch the ribosome in action, real small machinery, quick and precise, always in motion. Zoom in on the key step by which any protein gene becomes alive. Thanks to Ada Yonath, discover a close passage of any genetic information required to achieve useful functionality.

By her side, Puri García López, in an evolutionary approach starting from the current biodiversity, will discuss the ribosome as a living fossil at the crossroads in origins of life.

Thierry Naas will bring us back to everyday life, leading us to practical medical applications related to knowledge of the crystal structure of the ribosome. Which are the antibiotics that target the ribosome and block the growth of bacteria ? What medical perspectives can we expect in the future?

Purificación Lopez-Garcia
Researcher at CNRS, Unit of Ecology, Evolution and Systematics, University Paris-Sud
Thierry Naas
Lecturer - practitioner at the University Hospital of Kremlin-Bicetre, a member of the INSERM U914 - Mechanisms of emerging antibiotic resistance

Moderator: Emilie Cler, science journalist

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