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16th SCI-RSC Medicinal Chemistry Symposium


Sep 11, 2011 - Sep 14, 2011
Chuchill College Cambridge

16th SCI-RSC Medicinal Chemistry Symposium

Churchill College, Cambridge, UK
11-14 September 2011
Organised by SCI's Fine Chemicals Group and RSC's Biological and Medicinal Chemistry Sector

Synopsis

The organisers cordially invite you to the 16th SCI-RSC Medicinal Chemistry Symposium, Europe's premier biennial Medicinal Chemistry event, focussing on first disclosures and new strategies in medicinal chemistry. Reflecting current trends in medicinal chemistry and pharmaceutical research, the theme of the conference will be The Path Forward: Collaboration or Competition? The scientific programme features lectures on Enzyme Inhibitors, Ligands for Receptors and Ion Channels plus a Hot Topic late breaker session. In addition the meeting has a number of talks addressing key Enabling Processes and Technologies for the future of Medicinal Chemistry. There will also be Poster Sessions with a number of posters selected for Short Talks..

Programme

Please click here to view the second circular

Sunday 11 September

 

15.00   Registration and refreshments
18.30   Welcome BBQ

 

Monday 12 September

 

08.55

 

Welcome and opening remarks
Andrew Williams, Chair, Organising Committee

09.00

  Discovery of next generation glucokinase activators
Mike Waring, AstraZeneca, UK

09.45

 

Discovery and development of allosteric AKT inhibitors for the treatment of cancer
Phil Sanderson, Merck, USA

10.30  

Refreshments in marquee & Jock Colville

11:00  

Strategies to success - H-PGDS inhibitors for the treatment of inflammatory disorders
Sukanthini Thurairatnam, sanofi aventis, USA

11:45  

Bromodomains: a new class of epigenetic targets for small molecule drug discovery
Jason Witherington, GlaxoSmithKline, UK

12.30  

Poster Talk l (TBD)

12.45  

Lunch (in dining hall, coffee after lunch in marquee)

14:00  

Design and optimisation of new MEK inhibitors for the treatment of cancer
Robert Heald, Argenta, UK

14.45  

Cobicistat: a novel and selective pharmacoenhancer
Lianhong Xu, Gilead, USA

15.30  

Refreshments in marquee & Jock Colville

16.00  

Design of liver-targeted Stearoyl Coenzyme-A Desaturase (SCD) inhibitors for the treatment of diabetes
Renata Oballa, Xenon Pharma,USA

16.45  

Histone methyl transferases as epigenetic targets: inhibitors of SETD7
Paul Fish ,Pfizer, UK

17.30  

Poster Talk ll (TBD)

17.45  

Poster Session 1 and wine reception

19.00  

College Dinner with bar open till 24:00

 

Tuesday 13 September

 

09:00

 

GPCR structure based drug design using stabilised receptors (StaRs)
Miles Congreve, Heptares, UK
 

09:45

 

The discovery and evaluation of PF-3893787: a novel histamine H4 receptor antagonist
Charlie Mowbray, Pfizer, UK

10.30

 

Refreshments in marquee & Jock Colville

11:00

 

A medicinal chemistry journey from almokalant to AZD7009/ AZD1305 discovery of clinical candidates for treatment of atrial fibrillation
Annika Bj�re, AstraZeneca, Sweden

11:45  

Selective N-type calcium channel blockers for the treatment of pain
Ged Giblin, Convergence, UK

12.30  

Malcolm Campbell Award

12:45  

Lunch (in dining hall, coffee after lunch in marquee)

14:00  

Lilly�s Open Innovation Drug Discovery Initiatives: From Concept to Reality
Marta Pineiro-Nunez ,Lilly Research Laboratories, USA

14:45  

Cell-based optimization of novel antimalarials from HTS hit
Arnab Chatterjee, Genomics Institute of the Novartis Research Foundation, USA

15:30  

Refreshments in marquee & Jock Colville

16:00  

SAR and structural biology of Nek kinase inhibitors
Swen Hoelder, Cancer Research, UK

16:40  

CPHPC plus anti-SAP antibody: a first in class small molecule/antibody combination to eliminate systemic amyloid deposits
Mark Pepys, University College London, UK

17.20  

Now what? The state of drug discovery
Derek Lowe, Vertex, USA

18.00   Poster Session 2 and refreshments
19.30  

Pimms reception on college lawn

20:00  

Conference dinner

 

Wenesday 14 December

 

09:00

 

mGluR2 Positive Allosteric modulators
Jose Cid, Janssen R&D, Spain

09:45

 

Inhalation by design: discovery of slow offset muscarinic M3 receptor antagonists for treatment of COPD
Paul Glossop, Pfizer, UK

10.30

 

Refreshments in Marquee & Jock Colville

11:00

 

Poster Talk lll (TBD)

11.15  

Discovery of muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist (MABA) dual pharmacology molecules
Adam Hughes, Theravance, UK

12.00  

Development of urea-based LXR agonists
Jonathan Bennett, Merck, USA

12:45  

Lunch (in dining hall, coffee after lunch in marquee)

14.00  

Orally active TLR7 agonists for antiviral application
David Pryde, Pfizer, UK

14.30  

How a new class of antibiotic inhibits bacterial type IIA toposiomerases
Ben Bax, GlaxoSmithKline, UK

15.00  

Finding the Gini: brain penetrant kinase inhibitors for the treatment of neurodegenerative diseases
Piotr Graczyk, Eisai, UK

15:30  

Designing molecules outside the RO5
David Millam, Pfizer, UK

16:00  

Closing Remarks

 

Call for Papers

The poster session is an important part of the meeting and contributions from the whole field of medicinal chemistry are invited: a number of conference places will be reserved for poster presenters. Detailed procedures and deadlines for submission of poster and lecture abstracts will be given in the second circular. To receive the second circular, or request further information, please register with the secretariat at conferences@soci.org. Also Presentations are invited from potential contributors to the late breaker session, contributors should highlight this in their communications to the Secretariat.
 

Sponsorship & Exhibition

Churchill College is an ideal venue for an exhibition. All refreshments, lunches, the exhibition and posters are situated in a single area, ensuring excellent access to delegates throughout the meeting. If you are interested in sponsoring this event please contact jacqui.colgate@soci.org for further information and costs.


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