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News articles about "Conformational"

Visualizing DNA double-strand break process for the first time

Scientists from the Spanish National Cancer Research Centre CNIO led by Guillermo Montoya have developed a method for producing biological crystals that has allowed scientists to observe for the first time DNA double chain breaks ... - Read More

Charged graphene gives DNA a stage to perform molecular gymnastics

When Illinois researchers set out to investigate a method to control how DNA moves through a tiny sequencing device they did not know they were about to witness a display of molecular gymnastics Fast accurate ... - Read More

Decoding 'sweet codes' that determine protein fates

We often experience difficulties in identifying the accurate shape of dynamic and fluctuating objects This is especially the case in the nanoscale world of biomolecules The research group lead by Professor Koichi Kato of the ... - Read More

New details on microtubules and how the anti-cancer drug Taxol works

A pathway to the design of even more effective versions of the powerful anti cancer drug Taxol has been opened with the most detailed look ever at the assembly and disassembly of microtubules tiny fibers ... - Read More

New atom-scale knowledge on the function of biological photosensors

The research groups of Janne Ihalainen University of Jyväskylä and Sebastian Westenhoff University of Gothenburg have clarified how the atom structure of bacterial red light photosensors changes when sensing light The research reveals structural changes ... - Read More

Scientists decode serotonin receptor at room temperature

Serotonin
An international research team has decoded the molecular structure of the medically important serotonin receptor at room temperature for the first time This study reveals the dynamics of the receptor at close to its operating ... - Read More

Infrared sheds light on single protein complexes

Proteins are basic building blocks of life The chemistry and structure of proteins are essential for their biological function Indeed the structure of proteins determines their mechanical and catalytic properties e g enzymes Such functions ... - Read More

Molecular biology: Designer of protein factories exposed

Molecular biology
For 10 years Patrick Cramer and his colleagues at Ludwig Maximilians Universitaet LMU in Munich have probed the structure of RNA polymerase I a crucial cog in the machinery of all cells Now they unveil ... - Read More

Tiny tweezers allow precision control of enzymes

enzymes, Enzymes, Enzymes, Enzymes, Enzymes, enzymes
Tweezers are a handy instrument when it comes to removing a splinter or plucking an eyebrow In new research Hao Yan and his colleagues at Arizona State University's Biodesign Institute describe a pair of tweezers ... - Read More

Tiny nanocubes help scientists tell left from right

Chiral
In chemical reactions left and right can make a big difference A left handed molecule of a particular chemical composition could be an effective drug while its mirror image right handed counterpart could be completely ... - Read More

Comparing proteins at a glance: Technique for easy comparisons of proteins in solution

Proteins, Proteins, proteins
A revolutionary X ray analytical technique that enables researchers at a glance to identify structural similarities and differences between multiple proteins under a variety of conditions has been developed by researchers with the U S ... - Read More

Stressed proteins can cause blood clots for hours

Proteins, Proteins, proteins
New research from Rice University Baylor College of Medicine BCM and the Puget Sound Blood Center PSBC has revealed how stresses of flow in the small blood vessels of the heart and brain could cause ... - Read More

Microbial biorefinery provides new insight into how bacteria regulate genes

Genes, Bacteria, Genes, bacteria
Digesting lignin a highly stable polymer that accounts for up to a third of biomass is a limiting step to producing a variety of biofuels Researchers at Brown have figured out the microscopic chemical switch ... - Read More
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